The troops patrolling the Myanmar border noticed the truck in the village of Sri Pa Daeng (Moo 9) at 11.30pm and became suspicious.
As they approached, the driver sped away, triggering a chase and a call to local administrative officials and police to set up blockades.
The truck was soon found abandoned at the roadside in Sanna (Moo 2) in the same tambon, though the driver had vanished.
Inside the pickup were five sacks together containing a million meth pills.