Small doses of mRNA vaccines provide high immunity, low side effects, says virologist

FRIDAY, FEBRUARY 04, 2022
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In a Facebook post on Friday, leading virologist Dr Yong Poovorawan explained that many countries in the West are administering half the dose of mRNA vaccines as booster shots and that they are proving just as effective.

He said Chulalongkorn University’s Centre of Excellence in Clinical Virology has studied the administration of 10 micrograms of Pfizer subcutaneously and 15 to 30mcg through intramuscular injection. The centre has also studied the delivery of the full dose (100mcg) and half dose (50mcg) of Moderna vaccines.

Both studies revealed that immunity to both Delta and Omicron variants remains similar regardless of the doses.

He said vaccination centres under the Public Health Ministry, such as Bang Sue Grand Station, are administering Pfizer vaccines of 10mcg subcutaneously and 15-30mcg intramuscularly.

Yong said studies show that the administration of small doses reduces side effects but provides a high level of immunity.