This is according to a new report by staffing firm Kelly Services.
Hit by the global slump in commodities and manufacturing demand, three sectors featured in last year's top five list are out of this year's ranking: oil, gas and petrochemicals; pharmaceuticals; and semiconductors.
IT tops the 2016 list with technology heads expected to command between S$13,000 and S$24,000 a month, according to the Kelly Singapore 2016 Salary Guide.
Ths firm said the Government's aggressive infocomm sector development is behind the emergence of IT as one of the highest paying industries.
In terms of specific occupations, some of the hot jobs for 2016 are: compliance manager, fintech developer, big data developer, digital marketing manager and scientific and regulatory affairs specialist
Said Foo See Yang, vice-president and country general manager of Kelly Services Singapore: "Despite the challenges in the global economy, bright spots remain in the financial technology, big data, as well as digital marketing sectors where demand for talent will continue to rise throughout 2016.
"Professionals, managers, executives and technicians (PMETs) who have been hit hardest by the slowdown should look at upskilling and expanding their capabilities into new areas of growth to stay relevant."
The firm also said that global economic volatility will lead to more employers turning to temporary and contract work arrangements to fulfil manpower needs.
"There is a need for a mindset shift by the Singaporean workforce to look beyond permanent roles, especially in the current economic environment," said Foo.